{"id":1533,"date":"2025-06-14T21:00:09","date_gmt":"2025-06-14T13:00:09","guid":{"rendered":"http:\/\/www.cscai.cn\/?p=1533"},"modified":"2025-11-07T15:07:45","modified_gmt":"2025-11-07T07:07:45","slug":"%e5%a4%a9%e4%bb%b7cgt%e7%96%97%e6%b3%95%e7%9a%84%e6%94%af%e4%bb%98%e5%8d%9a%e5%bc%88%ef%bc%9a%e7%be%8e%e5%9b%bd%e5%8c%bb%e4%bf%9d%e5%a6%82%e4%bd%95%e4%b8%8d%e4%b8%ba%e6%97%a0%e6%95%88%e6%b2%bb","status":"publish","type":"post","link":"http:\/\/www.qlcxw.com.cn\/?p=1533","title":{"rendered":"\u5929\u4ef7CGT\u7597\u6cd5\u7684\u652f\u4ed8\u535a\u5f08\uff1a\u7f8e\u56fd\u533b\u4fdd\u5982\u4f55\u4e0d\u4e3a\u65e0\u6548\u6cbb\u7597\u4e70\u5355\uff1f"},"content":{"rendered":"<p>\u5f53\u5927\u897f\u6d0b\u4e24\u5cb8\u7684\u5fb7\u56fd\u4e0e\u7f8e\u56fd\u51e0\u4e4e\u540c\u65f6\u4e3aCGT\u7597\u6cd5\u652f\u4ed8\u5f00\u521b\u65b0\u6a21\u5f0f\uff0c\u53c8\u5c06\u4e3a\u4e2d\u56fd\u7684\u533b\u4fdd\u652f\u4ed8\u6539\u9769\u5e26\u6765\u600e\u6837\u7684\u501f\u9274\u4e0e\u542f\u793a\uff1f<\/p>\n<p>\u5728\u5404\u56fd\u533b\u7597\u8d39\u7528\u6301\u7eed\u6500\u5347\u4e0e\u6280\u672f\u8fed\u4ee3\u52a0\u901f\u7684\u53cc\u91cd\u6311\u6218\u4e0b\uff0c\u533b\u7597\u652f\u4ed8\u4f53\u7cfb\u7684\u6539\u9769\u5df2\u6210\u4e3a\u5168\u7403\u6027\u6311\u6218\u3002\u56e0\u6b64\uff0c\u9488\u5bf9\u5168\u7403\u516c\u8ba4\u7684\u6602\u8d35\u521b\u65b0\u7597\u6cd5CGT\uff0c\u5404\u56fd\u90fd\u8fdb\u884c\u4e86\u4e0d\u540c\u7684\u5c1d\u8bd5\u3002<\/p>\n<p>\u8fd1\u671f\uff0cCSL\u516c\u53f8\u5c31\u548c\u5fb7\u56fd\u533b\u4fdd\u673a\u6784\u8fbe\u6210\u4e86\u4e00\u4e2a\u521b\u65b0\u4ed8\u8d39\u534f\u8bae\uff1a\u5929\u4ef7\u57fa\u56e0\u836fHemgenix\u4e0d\u7528\u63d0\u524d\u5168\u6b3e\u4e70\u5355\uff0c\u800c\u662f\u201c\u6cbb\u597d\u4e86\u518d\u4ed8\u94b1\u201d\uff0c\u5f00\u521b\u4e86\u4e00\u79cd\u5168\u65b0\u7684\u201c\u98ce\u9669\u5206\u62c5\u201d\u6a21\u5f0f\u3002\u5177\u4f53\u6765\u8bf4\uff0c\u533b\u4fdd\u6bcf\u5e74\u4f1a\u6839\u636e\u5b9e\u9645\u6cbb\u7597\u6548\u679c\u652f\u4ed8\u836f\u8d39\uff0c\u5982\u679c\u6cbb\u7597\u5931\u8d25\uff08\u6bd4\u5982\u60a3\u8005\u53c8\u9700\u8981\u6253\u539f\u6765\u7684\u51dd\u8840\u9488\uff09\uff0c\u836f\u4f01\u5c31\u5f97\u81ea\u5df1\u627f\u62c5\u635f\u5931\uff0c\u533b\u4fdd\u4e0d\u7528\u4ed8\u94b1\u3002<\/p>\n<p>\u8fdc\u5728\u5927\u897f\u6d0b\u53e6\u4e00\u8fb9\u7684\u7f8e\u56fd\uff0c\u5373\u4f7f\u4f5c\u4e3a\u4e16\u754c\u6700\u5927\u7684\u533b\u7597\u5e02\u573a\uff0c\u4e5f\u672a\u80fd\u907f\u5f00\u6602\u8d35CGT\u7597\u6cd5\u7ed9\u4f20\u7edf\u533b\u4fdd\u652f\u4ed8\u6a21\u5f0f\u5e26\u6765\u7684\u4e25\u5cfb\u6311\u6218\u3002<\/p>\n<p>\u9762\u5bf9\u8fd9\u4e00\u538b\u529b\uff0c\u7f8e\u56fd\u533b\u7597\u4fdd\u9669\u548c\u533b\u7597\u8865\u52a9\u670d\u52a1\u4e2d\u5fc3\uff08Centers 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decoding=\"async\" class=\"image ext_img \" src=\"https:\/\/gbres.dfcfw.com\/Files\/iimage\/20250506\/0718F3302BC3135695E4D246AE7BD446_w246h246.png\" alt=\"\" data-imglabel=\"\" \/><\/p>\n<p style=\"text-align: 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Reduction Act, IRA\uff09\u5f3a\u5236\u836f\u4f01\u8fd4\u5229\uff08\u5982\u8d85\u51fa\u901a\u80c0\u7684\u6da8\u4ef7\uff09\u7b49\u63aa\u65bd\u5bf9\u4f20\u7edf\u836f\u54c1\u4ef7\u683c\u63d0\u4f9b\u4e86\u4e00\u5b9a\u7ea6\u675f\uff0c\u4f46\u516c\u5171\u533b\u4fdd\u9879\u76ee\u533b\u7597\u8d39\u7528\u4ecd\u5448\u6301\u7eed\u6500\u5347\u52bf\u6001\uff0c\u5c24\u5176\u5728\u7ec6\u80de\u4e0e\u57fa\u56e0\u7597\u6cd5\uff08Cell &amp; Gene Therapy, CGT\uff09\u7b49\u6602\u8d35\u521b\u65b0\u7597\u6cd5\u9886\u57df\uff0c\u652f\u4ed8\u6311\u6218\u4e25\u5cfb\u3002<\/p>\n<p>\u4e3a\u4e86\u5e94\u5bf9\u6311\u6218\uff0c\u7f8e\u56fd\u533b\u7597\u4fdd\u9669\u548c\u533b\u7597\u8865\u52a9\u670d\u52a1\u4e2d\u5fc3\uff08Centers for Medicare &amp; Medicaid Services, CMS\uff09\u4e8e2024\u5e7412\u67084\u65e5\u6b63\u5f0f\u542f\u52a8\u4e86CGT\u533b\u4fdd\u652f\u4ed8\u521b\u65b0\u8bd5\u70b9\u3002\u8be5\u8bd5\u70b9\u6253\u7834\u4f20\u7edf\u652f\u4ed8\u6a21\u5f0f\uff0c\u4ee5\u8054\u90a6\u5c42\u9762\u7684\u96c6\u4e2d\u8c08\u5224\u4e3a\u57fa\u7840\uff0c\u7ed3\u5408\u6309\u7597\u6548\u652f\u4ed8\u534f\u8bae\uff08Outcome-Based Agreement\uff09\u4e0e\u6761\u4ef6\u8fd4\u5229\uff08rebate\uff09\u673a\u5236\uff0c\u65e8\u5728\u4e3a\u53ef\u4ece\u6839\u672c\u4e0a\u6cbb\u6108\u7f55\u89c1\u75c5\u548c\u4e25\u91cd\u9057\u4f20\u75be\u75c5\u7684\u6602\u8d35\u521b\u65b0\u7597\u6cd5\u5efa\u7acb\u53ef\u6301\u7eed\u7684\u652f\u4ed8\u89e3\u51b3\u65b9\u6848\u3002<\/p>\n<p>\u6839\u636eCMS\u89c4\u5212\uff0c\u8be5\u8bd5\u70b9\u521d\u671f\u5c06\u805a\u7126\u9570\u72b6\u7ec6\u80de\u75c5\uff08Sickle Cell Disease, SCD\uff09\u7684\u4e24\u79cd\u57fa\u56e0\u7597\u6cd5\u2014\u2014Vertex Pharmaceuticals\u5f00\u53d1\u7684Casgevy\u4e0eBluebird Bio\u7814\u53d1\u7684Lyfgenia\u3002\u6b64\u7c7b\u7597\u6cd5\u8d39\u7528\u9ad8\u8fbe220\u4e07\u81f3310\u4e07\u7f8e\u5143\uff0c\u662f\u53f2\u4e0a\u6700\u6602\u8d35\u7684\u7cbe\u51c6\u6cbb\u7597\u836f\u7269\u4e4b\u4e00\u3002\u7136\u800c\u6839\u636e\u7f8e\u56fd\u75be\u75c5\u63a7\u5236\u4e0e\u9884\u9632\u4e2d\u5fc3\uff08CDC\uff09\u7684\u6570\u636e\u663e\u793a\uff0cSCD\u60a3\u8005\u4eba\u5747\u5bff\u547d\u8f83\u7f8e\u56fd\u5e73\u5747\u6c34\u5e73\u77ed20\u4f59\u5e74\uff0c\u4e14\u5176\u4e2d\u7ea650%\u4e3aMedicaid\u53c2\u4fdd\u8005\u3002\u5bf9\u4e8e\u8fd9\u4e00\u4f4e\u6536\u5165\u53ca\u5f31\u52bf\u7fa4\u4f53\u800c\u8a00\uff0c\u82e5\u65e0\u516c\u5171\u533b\u4fdd\u652f\u6301\uff0c\u60a3\u8005\u5c06\u65e0\u6cd5\u83b7\u5f97\u633d\u6551\u751f\u547d\u7684\u6cbb\u7597\u65b9\u6848\u3002SCD\u82e5\u672a\u5f97\u5230\u6709\u6548\u6cbb\u7597\uff0c\u4f1a\u4ea7\u751f\u4e00\u7cfb\u5217\u5e76\u53d1\u75c7\u5e76\u9020\u6210\u60a3\u8005\u53cd\u590d\u4f4f\u9662\uff0c\u8fdb\u4e00\u6b65\u52a0\u5267\u533b\u7597\u8d1f\u62c5\u3002<\/p>\n<p>CMS\u5e0c\u671b\u901a\u8fc7\u6b64\u6b21\u8bd5\u70b9\u89e3\u51b3\u6602\u8d35\u521b\u65b0\u7597\u6cd5\u7684\u53ef\u53ca\u6027\u95ee\u9898\uff0c\u786e\u4fdd\u4f4e\u6536\u5165\u7fa4\u4f53\u53ca\u65f6\u83b7\u5f97\u6b64\u7c7b\u5929\u4ef7\u6551\u547d\u836f\u3002<\/p>\n<p>\u6839\u636eCMS\u7f51\u7ad9\u53d1\u5e03\u7684\u9879\u76ee\u4ecb\u7ecd\u4e66\uff0c\u6b64\u6b21\u8bd5\u70b9\u7684\u6838\u5fc3\u76ee\u6807\u5728\u4e8e\uff0c\u4ece\u8054\u90a6\u5c42\u9762\u8fdb\u884c\u4ef7\u683c\u8c08\u5224\u3001\u7edf\u4e00\u5e02\u573a\u51c6\u5165\u6807\u51c6\u5e76\u7eb3\u5165\u6309\u7597\u6548\u4ed8\u8d39\uff0c\u6d88\u9664\u56e0\u5404\u5dde\u653f\u7b56\u5dee\u5f02\u5bfc\u81f4\u7684\u8986\u76d6\u4e0d\u5747\u7684\u95ee\u9898\uff0c\u4fdd\u969c\u6240\u6709\u53c2\u4e0e\u5dde\u7684Medicaid\u60a3\u8005\u53ef\u4ee5\u516c\u5e73\u83b7\u5f97\u57fa\u56e0\u6cbb\u7597\uff0c\u6700\u7ec8\u8fbe\u5230\u4eba\u7fa4\u5065\u5eb7\u6c34\u5e73\u4e0a\u5347\u7684\u76ee\u7684\u3002<\/p>\n<p>\u5177\u4f53\u800c\u8a00\uff0c\u8fd9\u4e00\u65b0\u652f\u4ed8\u6a21\u5f0f\u7684\u5b9e\u65bd\u65b9\u5f0f\u4e3b\u8981\u4e3a\u4e09\u6b65\uff1a\u8054\u90a6\u5c42\u9762\uff08CMS\uff09\u4e3b\u5bfc\u8fdb\u884c\u901a\u8fc7\u7edf\u4e00\u8c08\u5224\u4e0e\u5b9a\u4ef7\u3001\u8bbe\u7f6e\u5206\u5c42\u8fd4\u5229\u673a\u5236\u7b49\u65b9\u5f0f\u63a7\u5236\u4ed8\u8d39\uff0c\u6700\u540e\u5404\u5dde\u53ef\u81ea\u4e3b\u9009\u62e9\u662f\u5426\u53c2\u4e0e\u3002<\/p>\n<p>\u7edf\u4e00\u8c08\u5224\u4e0e\u5b9a\u4ef7\uff1a\u56e0SCD\u60a3\u8005\u7fa4\u4f53\u89c4\u6a21\u5c0f\u4f46\u6cbb\u7597\u6210\u672c\u6781\u9ad8\uff0cCMS\u9009\u62e9\u5148\u4eceSCD\u57fa\u56e0\u7597\u6cd5\u8bd5\u70b9\u3002\u5177\u4f53\u800c\u8a00\uff0cCMS\u4ee3\u8868\u5404\u5dde\u4e0e\u836f\u4f01\u8fdb\u884c\u96c6\u4e2d\u8c08\u5224\uff0c\u8fbe\u6210\u5168\u56fd\u7edf\u4e00\u4ef7\u683c\u548c\u51c6\u5165\u6807\u51c6\u3002\u4e3a\u786e\u4fdd\u534f\u8bae\u843d\u5730\uff0cCMS\u5c06\u63d0\u4f9b\u6280\u672f\u652f\u6301\uff0c\u8fdb\u884c\u76d1\u7763\u548c\u7597\u6548\u8bc4\u4f30\uff0c\u6838\u67e5\u5404\u5dde\u6267\u884c\u65f6\u7684\u5408\u89c4\u6027\uff0c\u5e76\u5efa\u7acb\u7597\u6548\u8ffd\u8e2a\u7cfb\u7edf\uff08\u7535\u5b50\u5065\u5eb7\u6863\u6848\uff09\u4ee5\u8bc4\u4f30\u8fd4\u5229\u89e6\u53d1\u6761\u4ef6\u3002<\/p>\n<p><img decoding=\"async\" class=\"image ext_img \" src=\"https:\/\/gbres.dfcfw.com\/Files\/iimage\/20250506\/5927DE40FFD77148EA5B7989921F9486_w832h382.png\" alt=\"\" data-imglabel=\"\u56fe1\uff1aCMS CGT\u51c6\u5165\u6a21\u5f0f\u5b9e\u65bd\u65f6\u95f4\u8868(\u6765\u6e90\uff1acms.gov)\" 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Drug Rebate Program, MDRP\uff09\u7684\u964d\u4ef7\u534f\u8bae\u4e0a\u8fdb\u4e00\u6b65\u964d\u4f4e\u4ef7\u683c\uff0c\u4f7f\u5f97\u65b0\u836f\u5728\u539f\u5148\u6298\u6263\u7684\u57fa\u7840\u4e0a\u8fdb\u4e00\u6b65\u4eab\u53d7\u65b0\u8c08\u5224\u5e26\u6765\u7684\u964d\u4ef7\u3002<\/p>\n<p><img decoding=\"async\" class=\"image ext_img \" src=\"https:\/\/gbres.dfcfw.com\/Files\/iimage\/20250506\/3FC71B224CF48B08186FCCA03BF3D846_w832h490.png\" alt=\"\" data-imglabel=\"\" \/><\/p>\n<p style=\"text-align: center;\">\u56fe2\uff1aCMS CGT\u51c6\u5165\u6a21\u5f0f\u8fd4\u5229\u7ed3\u6784<\/p>\n<p style=\"text-align: center;\">(\u6765\u6e90\uff1acms.gov)<\/p>\n<p><img decoding=\"async\" class=\"image ext_img \" src=\"https:\/\/gbres.dfcfw.com\/Files\/iimage\/20250506\/C8C33349B2D3FD7443540A6F95E72CB2_w798h252.png\" alt=\"\" data-imglabel=\"\" \/><\/p>\n<p style=\"text-align: center;\">\u56fe3\uff1aCMS CGT\u51c6\u5165\u6a21\u5f0f\u8fd4\u5229\u65f6\u95f4\u70b9<\/p>\n<p style=\"text-align: center;\">(\u6765\u6e90\uff1acms.gov)<\/p>\n<p>\u8bd5\u70b9\u7684\u5b9e\u65bd\u65b9\u5f0f\u4e0a\uff0c\u5dde\u653f\u5e9c\u5c42\u9762\u5219\u4f53\u73b0\u4e3a\u5404\u5dde\u81ea\u613f\u53c2\u4e0e\u673a\u5236\uff0c\u4fdd\u7559\u4e00\u5b9a\u81ea\u4e3b\u9009\u62e9\u6743\u3002\u5404\u5dde\u53ef\u4ee5\u81ea\u4e3b\u9009\u62e9\u662f\u5426\u53c2\u4e0e\u8bd5\u70b9\u8ba1\u5212\uff0c\u82e5\u52a0\u5165\uff0c\u5dde\u653f\u5e9c\u5c06\u76f4\u63a5\u91c7\u7528CMS\u4e0e\u836f\u4f01\u8c08\u5224\u8fbe\u6210\u7684\u7edf\u4e00\u4ef7\u683c\u53ca\u652f\u4ed8\u6a21\u5f0f\uff0c\u4e0d\u5f97\u53e6\u884c\u8bae\u4ef7\u6216\u4fee\u6539\u6838\u5fc3\u8fd4\u5229\u89c4\u5219\u3002<\/p>\n<p>CMS 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